pentobarbital will lower the level or effect of artemether/lumefantrine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Coadministration with robust CYP3A4 inducers may result in lessened serum concentrations and lack of antimalarial efficacypentobarbital will reduce the level or influence of conivapt… Read More